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whereas during the chronic phase, M2 markers, such as Arg1, are increased, but may promote intestinal fibrosis ( Amino acid metabolism plays a central role in macrophage polarization in MS and its animal model, experimental autoimmune encephalomyelitis (EAE)

Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis

It is also studied for activation of the FAK-paxillin pathway, which governs cell migration and adhesion

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Vitamin B 12 deficiency