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The standard schedule is a starting point, not a strict rule The 2024 NICE guideline NG239 on B12 deficiency in over 16s makes an important point: the optimal route, dose and frequency of B12 replacement have never been firmly established, and have often followed custom and historical practice

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always assess B12 directly

Malouf R, Evans JG
score 3: more than 50% higher cellularity of ribbon-oriented round nucleus cells
Homo-oligomerization of Marburgvirus VP35 is essential for its function in replication and transcription
