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Am J Physiol Cell Physiol 267: C1633C1640, 1994

This hypothesis is largely based on studies showing that exogenously added ROS induce inflammatory cytokines, while addition of antioxidants, including the main thiol antioxidant, glutathione (GSH), inhibits it

2,7,8 In a longitudinal memory clinic cohort, low plasma EGT predicted faster decline in multiple cognitive domains and functional measures over up to five years

The milligram dose reflects the mass of the peptide, not its biological activity

Further research led to the identification of a C-terminal clathrin binding domain, present in -Arrs that is necessary for endocytosis of GPCRs but not for phosphorylation-dependent uncoupling of receptors from heterotrimeric G proteins (Gagnon et al., 1998)