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But they are the exception, not the pattern

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In particular, elective procedures with high consequence complications, including TJA, warrant carefully designed observational cohorts with validated patient-reported outcomes, wound surveillance, and adverse event monitoring

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Mol Endocrinol 29, 411420 (2015)

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While it has shown promise in animal studies, its safety and efficacy in humans have remained uncertain due to a lack of robust clinical trials

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