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10.1016/j.micpath.2020.104700 [DOI] [PubMed] [Google Scholar] Svenson J, Karstad R, Flaten GE, Brandsdal BO, Brandl M, Svendsen JS

Immune Support: Strengthens the bodys natural defense system

Loomba et al

Price Comparison Framework Nasal Spray Pricing : Average cost: $45-$75 per bottle Typical concentration: 2.5-5mg total peptide Doses per bottle: 30-60 sprays Cost per dose: $0.75-$2.50 Higher upfront cost but better absorption Oral Capsule Pricing : Average cost: $35-$55 per bottle Typical concentration: 250-500mcg per capsule Capsules per bottle: 30-60 count Cost per dose: $0.60-$1.85 Lower initial cost but requires higher dosing True Cost Calculation The real value equation requires factoring in bioavailability differences: Example Scenario : Target systemic exposure: 200mcg absorbed Nasal spray (70% bioavailability): Requires ~285mcg dose = $1.40 per effective dose Oral capsule (40% bioavailability): Requires ~500mcg dose = $1.65 per effective dose When calculated based on actual absorbed peptide, the cost difference narrows considerably

ROS assay Intracellular ROS production was measured using the Image-iT LIVE Green Reactive Oxygen Species Kit (Invitrogen)