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Most are broken down rapidly by digestive enzymes, which is why nearly all peptide drugs require injection

In a recently published review, the advantages of eryptosis over hemolysis as a toxicological endpoint have been summarized, emphasizing that eryptosis in vitro testing has a higher sensitivity, is more accurate and reproducible, provides better quality control, and can shed light on the cytotoxicity-mediating molecular mechanisms compared with hemolysis [450]

Safety of long-term feeding of dl-alpha-lipoic acid and its effect on reduced glutathione:oxidized glutathione ratios in beagles

After efficient internalization of CDCZA nanoparticles by Eca-109 tumor cells, the released Cur could notably decrease intracellular GSH content and thus improve the chemosensitivity of CDDP, resulting in severe cellular apoptosis

The effectiveness of amyotrophic lateral sclerosis stem cell therapy varies from patient to patient, depending on factors such as age, disease stage, and individual immune response

The phenolic acids protocatechualdehyde, (E)-ethyl p-methoxycinnamate, and picein exhibit anticancer, anti-inflammatory, and antioxidant effects (7073)