is sublingual b12 as good as injections Vitamin vs. Oral Supplements: Which Do You Actually Need? B12 Under the Tongue: Uses,
Description
In adipose tissue (where NNMT is highly expressed), inhibition activates the polyamine flux pathway and shifts adipocytes toward a 'beige' phenotype with elevated energy expenditure

Once into the brain, Vit B12 interacts with genes (LRRK2), proteins (synuclein and Lewy bodies), neurotransmitters (dopamine, Acetylcholine (Ach)) and metabolites that do impact on CNS hemostasis

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Taking high-dose oral B12 supplements can also greatly increase blood levels here, the same period of 7-10 days should be observed before testing

It remains a research compound that some clinics and individuals have begun using despite the lack of regulatory approval

Typical MIC-B12 dosing varies by compound, indication, and individual factors
