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However, metformin inhibits mitochondria in a dose-dependent manner and at high doses, although it is able to impair tumor growth, it may also lead to lactic acidosis (116)

Neuropharmacology 19:163167 Bridoux A et al (2013) The acute inhibition of rapid eye movement sleep by citalopram may impair spatial learning and passive avoidance in mice

Inter-alpha inhibitor proteins attenuate lipopolysaccharide-induced bloodbrain barrier disruption and downregulate circulating interleukin 6 in mice

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