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Body composition in DIO mice with/without NNMT inhibition showing reduced WAT mass with preserved lean mass relative to diet-matched controls [1,3,4]

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The cells were lysed by ultrasound for 20 min at 4 C, followed by centrifugation at 12,000 rpm for 15 min to collect the supernatant

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Negative feedback in noncanonical NF-B signaling modulates NIK stability through IKK-mediated phosphorylation