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For example, activity-regulated cytoskeleton-associated protein (ARC), a synaptic protein critical for the internalization of -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking at synapses, is one mRNA target of FMRP at the synapses (Waung et al., 2008

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Note that we analyzed RPE1 cells in the current study and not HeLa cells, and perfect overlap is therefore not to be expected due to significant differences in protein abundances and hence phospho-signaling network activities between cell lines 23