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Brief Funct Genomics (2006) 5(4):24960

Manco M, Mosca A, De Peppo F, et al

Abnormal glucose metabolism: Research suggests sleep apnea can negatively affect glucose metabolism and lead to the development of diabetes

This leads to persistent fatigue, difficulty coping with stress, and a wide range of physical and emotional symptoms

compete with acetylcholine (ACh) for binding to postsynaptic nicotinic receptor sites SECONDARY MECHANISM: Nondepolarizing relaxants also from motor nerve endings by still poorly understood mechanism(s)

This damages melanocytes and interferes with melanin production
