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Serine supplies glycine and one-carbon units for de novo nucleotide biosynthesis in proliferating T cells, and one-carbon units from formate can rescue T cells from serine deprivation ( We previously reported that calcium/calmodulindependent protein kinase IV (CaMK4) binds to PKM2 and promotes pyruvate kinase activity

Iwegbulem O, Wang J, Pfirrmann RW, Redmond HP (2022) The role of taurine derivatives in the putative therapy of COVID-19-induced inflammation

RWC was measured as (FW DW)/(TW DW) 100

[Google Scholar] Boddy 1968 Boddy K, King P, Mervyn L, Macleod A, Adams JF

d 5 -JA was added to the extraction solvent (isopropanol: formic acid at 99.5: 0.5, v/v) as internal standard

Open field As described 65 , mice were habituated in the testing room under normal light for 1 h before testing