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Description

This review explores the complex mechanisms underlying DN and highlights recent advances in diagnostic and therapeutic strategies

Data Availability Statement Data sharing is not applicable to this article as no new data were created or analyzed in this study.

A study that analyzed data from 500 subjects taking low-dose opioids (mainly methadone [Methadose or Dolophine] or oxycodone [Oxycontin]) for long-term management of RLS suggested this approach can be effective (Winkelman 2021)

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Basically, L-Carnitine is responsible for transporting long-chain fatty acids into the mitochondria, where they are oxidised to produce usable energy in the form of adenosine triphosphate (ATP)