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Coleman and Haller, 2017

Free drug is rapidly removed from plasma, bound drug is released to maintain equilibrium and a concentration gradient is maintained between plasma and hepatocyte because drug is metabolised very quickly
Today, the best thing we can do is reduce oxidative stress, and the number one way to do that is improve glutathione

NQO1 comes into play in the phase II metabolism of benzene after it has been acted on by CYP2E1