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These conjugates are excreted into the duodenum via bile, where they are hydrolyzed back to GA by symbiotic bacteria, after which they can be reabsorbed (Figure 3)

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Protein Farnesyltransferase Inhibitor (Sch 66336) Abolishes Nf-Kappab Activation Induced By Various Carcinogens And Inflammatory Stimuli Leading To Suppression Of Nf-Kappab-Regulated Gene Expression And Up-Regulation Of Apoptosis

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Mohammad Z, Mitchell KG, Robb C, Tu J, Antonoff MB

doi: 10.1105/tpc.106.046953