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Our understanding of the humoral and neuronal systems that mediate the control of energy homeostasis has improved dramatically in the past few decades

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Phenolic compounds are the major plant-compounds known to have antioxidant activity, and they show a variety of structures, from relatively simple molecules (e.g., gallic acid, caffeic acid, hydroxytyrosol, etc.) to complex polyphenols such as tannins and flavonoids, Figure 3

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