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In conclusion, MAD may be a good alternative approach for patients refusing CPAP therapy or for those who prefer MAD due to the less-invasive nature of the device
We then explored two human MASLD datasets 38,39 and found that hepatic expression of NR1H3 is increased in individuals with MASLD Activity Scores (NAS) from 1 to 7, compared with those without MASLD (NAS = 0
Indeed, silymarin-loaded gold nanoparticle, orally administered in BDL-rats for 7 days, improved liver function, reducing transaminase, GT, and direct and total bilirubin serum levels, diminished oxidative stress markers both in serum and liver and, lastly, increased antioxidant support [198]

Pharm Ther 39(9):638645 Patrick L, Uzick M (2001) Cardiovascular disease: C-reactive protein and the inflammatory disease paradigm: HMG-CoA reductase inhibitors, alpha-tocopherol, red yeast rice, and olive oil polyphenols

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