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[DOI] [PubMed] [Google Scholar] 128.Jung B, Obinata H, Galvani S, Mendelson K, Ding BS, Skoura A, Kinzel B, Brinkmann V, Rafii S, Evans T, and Hla T
It is considered safe under medical supervision.

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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Efficacy of Repeat Immunoadsorption

Thats really simple
The NETs then activate factors XIIa and XIa of the coagulation cascade, which can cause microthrombi and secondary brain ischemia - and considerably secondary damage
