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(c) nuclear translocation of predominantly p65/p50 dimers to induce transcription of target genes, including well-established FLICE-like inhibitory protein (c-FLIP) and apoptosis protein inhibitors (c-IAP)

Single-nucleus RNA sequencing in cortical and subcortical white matter lesions of human brain samples of patients with MS revealed that upper-layer excitatory neurons in MS lesions upregulate genes involved in oxidative stress, mitochondrial dysfunction and cell death 216

Iran J Pharm Res 2019

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