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10.1016/j.bbrc.2015.01.072 159 SuyamaK.SilagiE

Accumulating evidence has highlighted that APAP-induced oxidative stress and mitochondrial dysfunction are the fundamental factors in the pathogenesis of APAP-associated liver injury (ALI)
Hence, it was not until 2009 when a harmonised definition was finally described [2]

J Chromatogr B Analyt Technol Biomed Life Sci 2015

For example, pathways involved in glutathione metabolism or GCLC regulation might also be modified in the cases, which would affect the sensitivity of PDX tumors to BSO

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