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[34] [75] Based on reviews of neuroimaging studies involving BED-diagnosed participants, therapeutic neuroplasticity in dopaminergic and noradrenergic pathways from long-term use of lisdexamfetamine may be implicated in lasting improvements in the regulation of eating behaviors that are observed

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The TRIUMPH-4 trial, focused on adults with obesity and knee osteoarthritis, reported results showing 28.7% mean weight loss at 68 weeks with the 12 mg dose

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A longitudinal study demonstrated that the levels of C18:0, L-C16:0, C18:2, and LAC decreased in the first-episode and recurrent patients after 8 weeks treatment (72)

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