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46 Due to its hydrophilicity, small molecular size, and positively charged surface, OTP exhibits enhanced mucosal permeability, enabling it to overcome mucociliary clearance and reach pulmonary lesions

The peptide upregulates VEGF expression in multiple cell types and enhances endothelial cell responses to VEGF signaling

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If a nucleotide in DNA is attacked, it can result in a mutation

Therefore, although some oligonucleotide products targeting NNMT have shown effectiveness in vitro and in animal experiments, to date, no oligonucleotide products targeting NNMT have been used in clinical trials

J., Whitehead, J