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Early research into the structure-function relationships of the GH molecule identified the C-terminal region, specifically residues 176191 as a domain with particular relevance to metabolic activity in laboratory models

doi:10.1210/endo.142.12.8522

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Minimal immunogenic potential: Long-term studies in rodents and primates report no antibody formation, suggesting a low risk of immune reactions following repeated exposure to the peptide

Population pharmacokinetic-pharmacodynamic modelling of tesofensine

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