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The most authoritative and contemporary definition was articulated in 2002 by a joint Food and Agriculture Organization (FAO) and World Health Organization (WHO) expert consultation, which described probiotics as live microorganisms which, when administered in adequate amounts, confer a health benefit on the host (15)

In the affected area of nervous tissue close to the occluded vessel, two distinct zones can be distinguished: infarction core (a zone of severe ischemia) and penumbra (a zone of moderate ischemia

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Drugs 81 , 389395 (2021)