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It is a synthetic 15-amino-acid peptide that has been studied for possible effects on tissue repair, inflammation, blood vessel formation, tendon and ligament models, gastrointestinal injury models, and wound-healing pathways

[Crossref] Robinson MB, Dowd LA (1997) Heterogeneity and functional properties of subtypes of sodium-dependent glutamate transporters in the mammalian central nervous system

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Because unbound drug concentration is determined by dosing rate and clearancewhich is not altered, in the case of these low-extraction-ratio drugs, by protein bindingincreases in dosing rate will cause corresponding changes in the pharmacodynamically important unbound concentration