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Iron overload promotes M1 macrophage polarization and increases the M1 macrophage markers levels (IL-6, IL-1, and TNF-), leading to synovial damage

Dietary Polyphenols: Regulate the Advanced Glycation End Products-RAGE Axis and the Microbiota-Gut-Brain Axis to Prevent Neurodegenerative Diseases

10.1016/j.biomaterials.2012.06.059 5 CogoA.NapolitanoG.MichoudM

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These phospholipids are specifically implicated because the double bonds contained within the PUFA chains make these phospholipids particularly susceptible to oxidation damage [102]

One enzyme identified within natto is Nattokinase, which forms as a result of the preparation process
