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These results, combined with the direct correlation of the expression levels of ELAVL1 with the genes of the malate-aspartate shuttle, as seen with the breast cancer transcriptome data, suggest that while citrate and malate are likely more dependent on KGA metabolism, fumarate and aspartate can be generated by glutamine metabolism from either isoform
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A recent report described a case of intraoral melanoma potentially linked to the use of a nasal spray containing Melanotan II [7]
