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Long-chain lipids are predominantly transported out of the intestinal absorptive cells into the lymphatic circulation [43] via a multistep process including micelle formation with bile salts, intracellular de-esterification, re-esterification, packaging into lipoproteins, and extrusion across the enterocyte basolateral membrane into the lymph [44, 45]

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After intravenous administration, DSIP was found to have significantly lowered pain levels in six of the seven patients.20 As with the sleep trials, we should spotlight the fact that this study had a very small sample size

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