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Those with higher ergothioneine levels showed: 50% reduced risk of cognitive decline over five years Better memory performance across all age groups Brain activity patterns more similar to younger individuals on cognitive tasks Professor Barry Halliwell, one of the worlds leading experts on antioxidants at the National University of Singapore, explained the mechanism: Ergothioneine gets into mitochondria and preserves mitochondrial function in disease

Barrea L, Balato N, Di Somma C, et al

The TCA cycle is an aerobic cycle, and therefore a lack of oxygen would preclude synthesis of succinyl-CoA and hence of heme

These findings highlight the ability of ectopic endometrial tissue to resist iron overload-induced ferroptosis and promote ectopic lesion growth by mediating local cellular ferroptosis in peritoneal fluid in patients with endometriosis

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, Sabaretnam, T
