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Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide a chain of four amino acids with the sequence Ala-Glu-Asp-Gly

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For example, exposing endothelial cells to MOTS-c in vitro attenuated dysfunction caused by oxidative stress, in part by activating AMPK and suppressing inflammatory pathways (such as the MAPK/NF-B pathway) in those cells

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