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Trimmed mean of M-values (TMM) normalization was performed during differential expression analysis with edgeR (v4.36.0)

Sagittal 4 m paraffin sections of the brain were mounted on slides, which were rehydrated and incubated in a citrate buffer at 95C for 30 minutes for antigen retrieval

The dosages that researchers used in these studies ranged from 336 mg daily of cinnamon extract to 1500 mg daily in capsule form over 6 to 24 weeks, indicating the need for further investigations to determine the right dosing and duration of therapy

Geographic disparities are pronouncedNorth Africa and the Middle East show the highest prevalence, while data remain sparse in lowincome regions [35, 38]

Nonetheless, even in these extreme cases, the solidification arrests were observed at the same temperatures as those recorded in more standard experiments, within uncertainty