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DOX-mediated nephropathy is caused by glomeruli destruction and tubule damage [2, 3]

In general, people with the following conditions should not take HCG injections: Asthma Hypersensitivity or sensitivity to HCG and its components Hormone-dependent cancer, which depends on a hormone for growth and/or survival, such as breast, ovarian, and prostate cancer

While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say