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10.1016/j.actbio.2025.01.036 43 JiaY.XuL.LengS.SunY.HuangX.WangY.et al (2025b)

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The agency notes that the peptide is highly susceptible to protein aggregation and the accumulation of peptide-related manufacturing impurities when formulated for injection, which can trigger massive, systemic immune system reactions in human patients

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