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The accumulating 1 -pyrroline-5-carboxylate can then be reduced to proline by the NADP(H)-dependent enzyme pyrroline-5-carboxylate reductase (PYCR or P5CR)

Quinone formation as dopaminergic neuron-specific oxidative stress in the pathogenesis of sporadic Parkinson's disease and neurotoxin-induced parkinsonism

To test this, a CXCR1-expressing cell line (chem-1 cells) was used to measure IL-8-induced calcium mobilization with/without N0362

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