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As previously mentioned, early studies using direct measurements in muscle after 14 days on 4 to 6 g of carnitine per day failed to show increases in the muscle carnitine concentration (4, 5)

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Therefore, it is speculated that ferroptosis may exert its pathogenic effect in SLE by excessive inflammation, which enhances immune response, leading to organ damage and clinical manifestations

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The researchers identified nineteen major in vitro metabolites, which were then synthesized, purified, and characterized

[DOI] [PubMed] [Google Scholar] McElwee M