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PMID: 22180495

The approach is also compatible with the controlled production in stirred tank bioreactors as recently demonstrated for cardiac and hematopoietic lineages 77,78 and will provide the field with a potentially game-changing resource to allow the development of clinical as well as screening platforms where the requirement will be in the millions of organoids rather than todays laboratory scale

[DOI] [PubMed] [Google Scholar] 39.Matsumura K, Nakase E, Haiyama T, Takeo K, Shimizu K, Yamasaki K, Kohno K

Navarro-Sastre, A

This is particularly significant given that sex differences are observed in response to some drugs, including the prevalence of adverse events (Anderson, 2005
