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Despite some evidence suggesting that pelleted formulations of cuprizone can be less effective 27,28 , the use of cuprizone in a pelleted form is growing in popularity, with many research groups successfully utilising the pelleted form at chronic timepoints 29,30,31,32,33,34,35,36

This may be due to liver or kidney disease, or certain cancers and blood disorders: The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis

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Often called a Myer's Cocktail

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