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The cells of the respiratory epithelium collaborate to heat, hydrate and remove incoming particles

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However, many reported GSH-responsive systems demonstrate incomplete drug release under physiological intracellular GSH levels (110 mM), suggesting an overestimation of redox sensitivity in vitro

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However, metagenomic studies carried out on healthy vs acneic skin suggest that the imbalance in C.acnes strains diversity, and not in the absolute density of C.acnes , is responsible for acne pathogenesis [34]

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