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Figure 2 Inflammatory signaling in the CNS is often mediated by the NLRP3 inflammasome

Proc Natl Acad Sci USA 110(14):53925397 Li F, Patra KP, Yowell CA, Dame JB, Chin K, Vinetz JM (2010) Apical surface expression of aspartic protease Plasmepsin 4, a potential transmission-blocking target of the plasmodium ookinete

10.1126/scitranslmed.aaf1059 Sci Transl Med

Therefore, with the deepening of research, the regulatory pathways of ferroptosis in the antioxidant system are not limited to GSH-dependent antioxidant pathways, but also can play a role in regulating ferroptosis through GSH-independent antioxidant pathways, which means that there may be more regulatory mechanisms related to ferroptosis waiting for us to further explore

G., Yolken, R