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Science 362 , eaar3213 (2018)

Additionally, reversing thiol deficiency and restoring the thiol-disulfide balance that reduce disulfide accumulation and inhibit oxidative damage, which can impede the damage caused by ischemic stroke (Bektas et al., 2016)

These effects (i.e., rapidly reestablished reorganized blood flow) attenuated/eliminated the lesions in the brain (intracerebral and intraventricular hemorrhage), heart (congestion, myocardial infarction, severe arrhythmias), lung (hemorrhage), and congestion in the liver, kidney, and gastrointestinal tract [52,53]
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CICD has the potential to overcome the limitations of standard lung cancer treatments through anti-apoptotic bypass and modulation of the TME, providing a therapeutic target
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