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glutathione s-transferase mu 1 function transferases as mediators of signaling pathways involved in cell proliferation and cell death Frontiers | Glutathione S-Transferases: Role
Description
Although the potential contribution of the TME is considered in mediating the observed in vivo effects, further research is needed to address the complex mechanisms altering these treatment responses

B.KaraouiL

This mechanism is critical in acetaminophen overdose, where the toxic metabolite NAPQI depletes hepatic glutathione N-acetylcysteine administration replenishes GSH and prevents liver failure

This process consumes large amounts of arginine and increases ornithine secretion

PLoS One 10 (6), e0131827

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