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It consists of the 1, 2, and 3 extracellular domains, a transmembrane domain (encoded by exon 5), and a cytoplasmic tail (encoded by exons 6-8)

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Epub 2003/12/31

When BPC-157 binds to VEGFR2 on endothelial cells, it triggers downstream signaling (Akt and eNOS activation) that promotes the formation of new blood vessels