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Compared to mice with a global alcohol dehydrogenase 2 gene knockout ( Aldh2) , which exhibit remarkably higher blood acetaldehyde concentrations following acute oral alcohol administration than wild-type controls, mice with hepatocyte-specific Aldh2 deletion showed only about a 50% increase in systemic acetaldehyde (123)

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While short-acting versions like daily injections may better control postprandial glucose levels, they have largely been replaced by long-acting alternatives such as semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound), which only require weekly injections

Refrigerate at 2-8C, protect from light and heat, track the beyond-use window, and avoid freeze-thaw cycling

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