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The JAKSTAT is a critical pathway that responds to and mediates inflammatory molecules, which is significantly upregulated in glomerular cells of DN patients and is negatively associated with eGFR

Reversible skin and mucosal hyperpigmentation are the most commonly found skin manifestations of vitamin B12 deficiency [6]

Integration of MSC-derived exosomes with scaffold biomaterials has been shown to attenuate fibrosis by downregulating key profibrotic genes (COL1A1, COL5A2, and -SMA) through inhibition of the TGF-/Smad and YAP/TAZ signaling pathways

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It has been hypothesized that the introduction of the peptide may have enhanced the normoglycemic rate and potentially improved the function of transplanted islet grafts