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Consistently, we found that depleting KG either through inhibition of wildtype IDH1 or glutamine starvation, or inhibiting KGDD activity via exogenous succinate, sensitized CCNE1-driven cells to DNA damaging agents ( Fig

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Mesenchymal stem cells (MSCs) : MSCs can differentiate into neuronal cells and secrete neurotrophic factors like NGF and BDNF

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However, insulin can stimulate carnitine transport to skeletal muscle [272], which is associated with the upregulation of OCTN2 transcript levels [273]