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Contradictory or context-dependent effects Even though Nrf2 activation is generally cytoprotective in oxidative and electrophilic stress models, the pathway is highly context-dependent and may have some negative outcomes

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457 Currently, prodrug technology has been successfully employed with a diverse range of antiviral drugs, including those targeting HIV, SARS-CoV-2, and hepatitis viruses (such as HBV and HCV)

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