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Despite the lack of reliable a-synuclein tracers, as opposed to histopathological studies, functional neuroimaging enables longitudinal monitoring of disease mechanisms along with symptom progression, thereby providing tools that increase diagnostic accuracy (Pagano et al

Some studies combine neuroimaging (such as fMRI) or biomarkers, but there is a lack of unified standards for detection methods and time points

Besides, with help of a laser, the AIE-active conjugated polymer could be a tight junction modulator, helping to disrupt the tight junction and making this nanorobot cross the BBB easier

[DOI] [PubMed] [Google Scholar] 161.Jung KA, Kwak MK

doi: 10.1016/j.ejps.2014.09.012 118 GuiZZhuJYeSYeJChenJLingYet al

Expert Opinion on Therapeutic Targets, 20(10), 12591265