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GSH depletion may play a central role in inflammatory diseases and COVID-19 pathophysiology, host immune response and disease severity and mortality

However, this is a mixed observation, and careful monitoring in research protocols is key
Though standard treatments improve outcomes, they also pose risks such as nephrotoxicity, inflammation, and drug resistance, particularly to allopurinol [105,106]

The strength of evidence depends on the specific application you're considering

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