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The NADH produced in the cytosol by ADH must be reduced back to NAD + via either the malate-aspartate shuttle or the glycerol-phosphate shuttle
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Regarding glucose metabolism, astrocytes are a primary site for glycolysis and provide neurons with glycogen and lactate, and the astrocyte-neuron lactate shuttle model (ANLS) is critical for neuronal activity (Herrera Moro Chao et al., 2022)
