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Circulating levels decline with age, from roughly 200 ng/mL at age 20 to about 80 ng/mL by 60

Pet owners should consult licensed veterinarians for diagnosis and treatment of orthopedic conditions in their animals

That said, the compound has not been through full Phase III trials or FDA drug approval

High-dose oral therapy (10002000 micrograms daily) can be effective even in pernicious anaemia, as approximately 1% of B12 is absorbed through passive diffusion independent of intrinsic factor

This makes it a promising therapy for digestive disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and leaky gut syndrome (intestinal permeability)

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